Dogs Allergic to Vaccinations Needed for Study

Researchers at Purdue University hope to isolate the cause of allergic reactions to vaccinations in dogs.

Posted: January 11, 2008, 5 a.m. EST

Purdue University School of Veterinary Medicine is conducting a study to investigate the cause of allergic reactions in dogs after they have been vaccinated and researchers are seeking dogs to participate in the study.

Allergic reactions are the most common adverse side effects from canine vaccinations, according to the university. Typical reactions include swelling around the eyes and face, small swellings on the surface of the skin, generalized itching, and vomiting. Purdue’s recent research has shown that small dogs in general, along with several specific breeds have a significantly greater risk of having a reaction.

Forty-two breeds were analyzed, and Dachshunds, Pugs, Boston Terriers, Miniature Pinschers, and Chihuahuas experienced the highest rate of adverse reactions. Those breeds, along with Boxers, Australian Terriers, and Kerry Blue Terriers are sought for the study. All dogs must have been vaccinated within three weeks to qualify for the study.

Researchers are particularly interested in dogs – and their relatives – who have had allergic reactions. Researchers will study antibodies in high-risk dogs who have had allergic reactions and compare those samples to dogs of the same breed who have not. Through the study, researchers hope to isolate the vaccine components responsible for the allergy.

To participate, veterinarians must collect serum from the dog. Pet owners can refer their veterinarians here for collection instructions. Researchers will mail veterinarians postage-paid mailers to send in the samples. Dog owners must sign a consent form in order for their dogs to participate. Samples will be collected through 2008.

The study is funded by the American Kennel Club Canine Health Foundation.


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Romina   Pittsburgh, PA

5/27/2009 5:27:02 AM

I have a 5 year old Papillon. I only ask for the rabies shot, one vet told me that as long as he's an indoor dog he doesn't need the other
What my Papillon get is a sudden onset of vomiting and diarrhea, all at the same time. The vet's have given him a shot of Benadryl and corticosteroids. His face itches for hours after that and he can't seem to sit still.

I was once told by a vet that my dog didn't need the Benadryl or the steroids and that he was going to be fine (second time he had this problem). I'm glad I waited in the waiting room of his office before we went home because his problem showed up right
I hope that someday they find a safe vaccine. Thanks for the article!

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Elizabeth   Saint Louis, MO

11/4/2008 10:05:46 AM

My 12 lb terrier mix was given his yearly shots yesterday and by this morning (5 a.m.), he was in terrible pain. He cries when you touch him under his legs but did eat and drink some water but it's now noon and he is in his bed with a blanket over his body. I'm very worried about him because he is usually very active and always wants to be in the same room. I gave him the tiny person aspirin (sp?) and 1/2 of a Bendytrl (sp?) this morning nad called the vet's office and talked with a vet tech. They said to just watch him and they will call to check on him this evening. Any suggestions? He is a rescue dog and is about 4 years old. We adopted him almost 1 year ago so this is his first time with us for shots. We did give him the 3 year rabies which I will never do again! Thanks!

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nathan   somewherein, OH

1/11/2008 10:16:25 AM


John 3:16

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Cheryl   Conway, MO

1/11/2008 7:42:18 AM

My Boston has had a reaction before, and I do hope that they will find a way to give a safer vaccine.

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