Mary Sioux Falls, SD 7/8/2010 12:13:09 PM We tried Acepromazine with our dog because he had large thorns stuck in his skin from rolling around in the woods. He did relax and allow us to pull out the thorns but the next day he had a fairly serious seizure. I would not give my dog this drug again. He is an otherwise healthy 6 year old Portuguese Water Dog and an important part of our family. Not worth the risk.