Brian Victoire, North Dakota 12/7/2015 12:23:34 PM We have use acepromazine on two days. However, we used 1/3 of the prescribed dose and noticed no problems with it. Our dog was right beside us in the car, so I could monitor her at all times. We tried getting her slowly used to car travel but that did no good. She came out of it right away when we got to our destination and was fine. She is not a nervous dog except when she would have to travel in the vehicle.