Kidney Disease in Dogs

Leslie Sinclair, DVM explains how this disease can strike your dog at any age.


Q. What caused my dogs chronic kidney failure, and how is it treated?

Leslie Sinclair, DVMLeslie Sinclair, DVM says: Chronic kidney failure can occur in dogs of any age, but the likelihood increases with age. Over time, kidneys begin to lose their function and shrink in size. The kidneys compensate for decreasing function until they have very little ability to work, and then they begin to fail. Kidney transplantation is available for cats and has been explored for use in dogs, but the cost and complications associated with transplant rejection, as well as the ethical considerations associated with identifying a donor dog and extending the life of an elderly dog, make it an unrealistic option for now.

The most common symptoms of kidney failure are increased urination and increased thirst, known in medical terms as polyuria and polydypsia, or PU/PD. Once the condition advances to the point that the kidneys are no longer able to filter ammonia (a by-product of the breakdown of protein in the diet) from the bloodstream, the dog develops uremia, a toxic condition characterized by nausea and vomiting. A veterinarian analyzes a blood sample to further assess the degree of kidney failure. The most widely used indicators are the blood urea nitrogen (BUN) and creatinine values. Both of these are products of digestion that build up in the bloodstream when the kidneys are functioning poorly. The degree to which the BUN and creatinine values are increased correlates with the level of kidney failure.

Kidney damage cannot be reversed, but there are supportive measures that allow a dog with kidney failure to live comfortably, sometimes for years after the condition is first diagnosed. Dogs suffering from kidney failure are often dehydrated when diagnosed, and intravenous fluids are used to reverse the dehydration and reduce the amount of ammonia-like products in the dogs bloodstream. Antinausea medications can reduce vomiting and discomfort caused by uremia. Many dogs with kidney failure are anemic (lacking an adequate number of red blood cells) because they cannot produce a sufficient amount of the hormone erythropoietin, which is made by the kidneys and regulates the production of red blood cells by the bone marrow. Some dogs become so anemic that they require a blood transfusion or medication to stimulate their body to produce more red blood cells.

Because the blood circulating in a dogs body must go through the kidneys, the narrowed pathways found in damaged kidneys may cause a dog to have high blood pressure. This aspect of kidney failure has not yet been well studied because blood pressure measurement is difficult in dogs. As better equipment becomes available for monitoring dogs blood pressure, improved recognition and treatment will be available.

Once a dogs condition has stabilized, the veterinarian recommends a diet low in protein to prevent symptoms from reoccurring. If your dog develops chronic kidney failure, closely monitor him at all times, and work with your veterinarian to provide your dog with the best possible quality of life despite this irreversible condition.

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Reprinted from Ask the Vet About Dogs, by Leslie Sincliar, DVM © 2003. Permission granted by BowTie Press.


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sha   chicago, Illinois

12/18/2014 6:59:57 PM

Our beloved beagle passed away today from a long year with kidney disease. He was only 6yrs old. He received IVs throughout the year, meds, low protein diet, liver treats, distilled water. He fought to become his energetic misbehaved self, but the condition overwhelmed him. Today, I thank him for being a part of our family. Now may you rest in peace.

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Joan   Singapore, International

2/3/2014 12:41:56 AM

My dog was 17. He was eating well. I brought him to the vet on By Sun morning, before he could go for hydrotherapy. The vet said his kidneys failed and the BUN was 70. He said my dog should have an IV. By sun morning, he passed on. The vet claimed that my dog was very weak, had heart problems and suffered a heart attack. They supposedly tried to resuscitate my dog twice but his heart gave up. Could you advise if there has been any lapses while they were treating my dog? After the IV, my dog was supposed to return home on sun evening but he passed on.

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Melissa   Wake Forest, North Carolina

12/29/2013 11:15:11 AM

My baby has also been diagnosed with kidney failure. Within three days of eating a duck jerky from China he was the same way. @Monica the doctor gave him a week to live at Halloween and he has made it to Christmas. I have been administering IV fluids, amphojel (an antacid medication), K/D prescription diet and Ensure. Always keeping fresh water is important too. I think he is in his last week. I love him so much and will miss him horribly.

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Lille   Woddbridge, Virginia

5/28/2013 6:30:37 PM

My dog, Ganja Mon, died the same way. Your blog made me feel for you. I also have my baby's ashes in a box with a picture

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