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Dog Reactions to Vaccines

A veterinarian explains what you should know about the unwanted side effects of vaccinations for dogs.

Leslie Sinclair, DVM

Q. Can vaccines make my dog sick?

Leslie Sinclair, DVMLeslie Sinclair, DVM says: Yes, despite the enormous good they do, vaccines can have unwanted effects. Any dog can have an allergic reaction to a vaccine. The reaction usually occurs within a few minutes to hours after vaccination, and symptoms can range from vomiting and diarrhea to swelling around face and head (hives) to shock. Emergency treatment may be necessary to save the dogs life. Another condition that vaccination can trigger is autoimmune hemolytic anemia (AIHA). It occurs when, for any number of reasons, your dogs immune system turns on itself, and mistakenly begins to devour the red blood cells in her bloodstream. Vaccination is only one possible cause of AIHA, which can occur in dogs, humans, and other species. Most cases of AIHA respond successfully to medical treatment. Be sure to consullt your veterinarian about other causes of AIHA.

Vaccination is one of the most effective methods we have for protecting dogs, although rare adverse reactions do occur. Its important that you and your veterinarian carefully discuss which vaccines are truly necessary, and the benefits and drawbacks of vaccination.

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Reprinted from Ask the Vet About Dogs, by Leslie Sincliar, DVM © 2003. Permission granted by BowTie Press.

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Reader Comments
My little shih-tzu is just shy of 4 months old. At the vet's advice, he got a distemper and a rabies shot on Saturday (this is now Wednesday). He threw up last night and now he's not eating. I'm so upset and now I'm reading things on the internet that say that the two shots never should have been given at the same time and that the rabies shot is the same amount no matter the size of the dog. Duffy is only 6lbs.4oz. I'm so upset over this.
Virginia, Milton, DE
Posted: 12/21/2011 8:19:43 AM
We took our little Papillion in for her second set of shots. Our breeder took her for the first set. She did a lot of whining when she got the combination shot in her shoulder, but our vet said that is not uncommong for puppies. After rubbing it for about a minutes, she seemed okay. We left the vet's office and got about ten minutes away and she started yelping and twisting out of control. We turned around and went back to the vet and as we pulled in the parking lot, she vomited and went limp. They rushed her into a room and began giving her fluids and a shot of a steroid. After about fifteen minutes, she began to get color back in her gums and after another fifteen minutes she seemed all right and we brought her home. The next day she acted painful and after another day, she could hardly stand to move. We rushed her to an emergency vet clinic and they diagnosed her with vaccine induced meningitis. She has been on a tapering does of steroid for over two weeks and the care of a neurologist and now and seems to be all right. Her neurologist says they will have to be done with prior treatment of medication and only one vaccine given at a time with four weeks duration between vaccines. We do not know what to do about further vaccinations.
Vivian, Westervile, OH
Posted: 2/3/2010 7:02:13 AM
Just experienced a bad allergic reaction today. As soon as my dog got her shots, she vomited. Her face swelled up 2 hrs later, and she vomited one more time. Vet gave her another shot (poor dog had so many shots today), and we'll see if she gets better. Told me that she can die from such severe reactions. Makes me think twice about vaccinating her next time, if I can skip it, I will. Can't stand to see her in so much pain, not to mention losing her.
Irene, Kent, WA
Posted: 7/26/2009 10:48:05 PM
I have first hand knowledge of bad reactions to vaccine with my dog. It took only 20 mins. to show up. By the time I got back to the vetsmy IG had lumps all over his body. they give him a shot and said to wait 20 mins to see if the shot worked. I will not be taking him back any time soon. THe dog is eight years old.
Chris, pennsauken, NJ
Posted: 8/13/2008 5:45:25 PM
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